hrp0095p1-22 | Bone, Growth Plate and Mineral Metabolism | ESPE2022

Resolution of severe constipation following a switch from calcium carbonate to recombinant human PTH therapy: A case report

Apperley Louise , Jarvis C , Ramakrishnan Renuka

Hypoparathyroidism is treated with oral calcium carbonate and vitamin D analogues to increase serum calcium levels. Recombinant human parathyroid hormone (rhPTH) therapy can be considered in patients with poorly controlled hypocalcaemia or side effects to conventional treatment. Constipation, a known side effect of calcium carbonate, is often easily managed with simple laxatives. We describe resolution of severe constipation by changing conventional treatment to rhPTH. A femal...